One one hand, sending everything to indexers who then moderate and distribute the content gets over one of the biggest pain points of Mastodon, discoverability. Like, setting up a standalone instance in this service requires active effort to communicate with other instances to avoid them not becoming a ghost town. On the other, if you need that sort of centralization for distribution, it's hard to see why any federated or decentralized network would work for you over something like Twitter.
The social network of the future: No ads, no corporate surveillance, ethical design, and decentralization! Own your data with Mastodon!